The effects of melatonin on signaling pathways and molecules involved in glioma

Fundamental and Clinical Pharmacology just published my editorial on the role of melatonin in brain cancers, especially glioblastoma, looking at the role melatonin can play in its treatment, including decreasing proliferation and migration.

Glioblastoma multiforme (GBM) is still a devastating diagnosis. Patient mean survival time from diagnosis is little more than one year and fewer than 5% of GBM patients survive 5 years. GBM often spread along neurons and blood vessels, leading to diffuse spreading across brain tissue. This proliferation is driven by glioblastoma stem-like cells...

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#biomedical #glioblastoma #melatonin